250g NR Powder (Nicotinamide Riboside Chloride), 98% Purity (CAS 23111-00-4)
The AFEGA anti-aging shop will gradually include all (especially of course the scientifically proven effective) anti-aging substances in its program. According to studies by Prof. David Sinclair, the three most effective anti-aging substances are currently NMN (nicotinamide mononucleotide), resveratrol (the so-called 'red wine molecule') and metformin (EU-approved and approved as a diabetes drug). However, especially in the USA, there is a kind of 'war of faith' between two groups, which differ in their conviction as to which of the two substances (NR = nicotinamide riboside or NMN = nicotinamide mononucleotide) is the most effective anti-aging substance. We follow (of course) the assessment of Prof. Sinclair, and for David, NMN is clearly the more effective substance.
However, there is a significant argument that is made by the supporters of NR and is difficult to refute: for NMN, there are still no studies on humans. For NR already. Here is the title of an article in the journal nature from the year 2018, presented in a YouTube video by Dr. med. Ford Brewer:
See an excerpt from a recent YouTube interview with Prof. Sinclair.
The most important finding from the interview with Prof. Sinclair is that the minimum dose of NR is 400 mg per day. A study cited in the interview shows that these 400 mg are a kind of threshold and there is no effect of NR below this threshold.
Regarding security of NR see the current assessment of European Food Safety Authority